• What to Add When Methotrexate Fails...

    Added On : 18th July 2013

    What to Add When Methotrexate Fails in Rheumatoid Arthritis Patients

    Allan S. Brett, MD

  • Isolation for MRSA Isn't the Answer

    Added On : 5th July 2013

    Patricia Anne Kritek, MD, EdM

  • Metformin vs. Glipizide for Patients...

    Added On : 21st June 2013

    Metformin vs. Glipizide for Patients with Diabetes and Coronary Disease

    Metformin was associated with better cardiovascular outcomes.

  • Considering CRP Concentration Improves Diagnosis...

    Added On : 7th June 2013

    Considering CRP Concentration Improves Diagnosis of Pneumonia

    Low C-reactive protein levels helped rule out pneumonia.

  • Steroid Injection Is Effective for Some Patients...

    Added On : 25th May 2013

    Steroid Injection Is Effective for Some Patients with Morton Neuroma

    But the durability of the effect is unclear.

  • Fundoplication vs. Optimal Medical Management...

    Added On : 11th May 2013

    Fundoplication vs. Optimal Medical Management for Chronic GERD

    In the long run, patients with gastroesophageal reflux disease experienced greater improvements with surgery.

  • TNF Inhibitors Are Associated...

    Added On : 28th April 2013

    TNF Inhibitors Are Associated with Higher Risk for Melanoma in Rheumatoid Arthritis Patients

    Absolute risk was small, but relative risk was increased by 50% in patients treated with tumor necrosis factor inhibitors.
    Immune deficiency states, such as immunosuppression for organ transplantation, are associated with elevated risk for malignant melanoma. Although use of tumor necrosis factor α (TNF) inhibitors (e.g., infliximab [Remicade]) raises risk for opportunistic infections, whether their use is associated with excess risk for melanoma is unclear. In this population-based cohort study from Sweden, investigators evaluated the association between TNF inhibitor use and melanoma in patients with rheumatoid arthritis (RA).

  • Prostate Cancer Screening: One More Take

    Added On : 15th April 2013

    The American College of Physicians has issued guidance for clinicians.

    The American College of Physicians (ACP) has issued a new publication on prostate cancer screening, focusing mainly on prostate-specific antigen (PSA) testing. The statement begins with a synopsis of four published guidelines — those of the U.S. Preventive Task Force, American Cancer Society, American Urologic Association, and American College of Preventive Medicine — and ends with two "Guidance Statements." Along the way, the authors briefly review the evidence for and against screening, and list ten talking points for use in discussions between clinicians and patients.

  • Intensive Glycemic Control and End-Stage Renal Disease...

    Added On : 2nd April 2013

    Intensive Glycemic Control and End-Stage Renal Disease in Type 2 Diabetes

    One case of ESRD was prevented for every 430 intensively treated patients.

  • Can We Perform Fewer Head CTs...

    Added On : 19th March 2013

    Can We Perform Fewer Head CTs in the Emergency Department?

    Perhaps, but crafting a good decision rule for computed tomography isn't easy.