Interventions to Reduce Worm Infections and Their Impacts
In China, school-based educational activities led to reduced prevalence of worm infection; in India, 6-monthly deworming had little effect on mortality or weight in young children.
Neuraminidase Inhibitor Resistance Uncommon with Latest Pandemic Influenza A Strain
Although little NAI resistance was seen in the most-recent pandemic influenza A strain (H1N1pdm2009), it was detected in a few patients — mainly young children — after oseltamivir treatment.
Human herpesvirus 6 can cause encephalitis early after allogeneic hematopoietic stem cell transplantation.
Human herpesvirus 6 (HHV-6) causes benign febrile illness or rash in >95% of children. It remains latent in the body thereafter but can become reactivated in severely immunocompromised individuals. Noting reports of HHV-6–associated neurologic disease in patients who had undergone allogeneic hematopoietic stem cell transplantation, investigators in Maryland undertook a retrospective investigation involving adults who underwent this procedure at the National Institutes of Health Clinical Center between 2009 and 2011.
Children aged 6 years with community-acquired pneumonia who were receiving a ?-lactam and a macrolide had shorter hospital stays than those receiving a ?-lactam alone.
Experts disagree as to whether single (?-lactam only) antibiotic treatment is optimal for children hospitalized with community-acquired pneumonia (CAP) or whether adding a macrolide is preferable. (Study findings regarding adults vary, but some favor combination therapy.) In a recent Infectious Diseases Society of America guideline, ?-lactam monotherapy is recommended. To explore this issue further, researchers used data from 38 freestanding tertiary care children's hospitals, obtained from the Pediatric Health Information System.
