Effects of Patient-Directed Music Intervention on Anxiety and Sedative Exposure in Critically Ill Patients Receiving Mechanical Ventilatory Support
A Randomized Clinical Trial
Linda L. Chlan, PhD, RN; Craig R. Weinert, MD, MPH; Annie Heiderscheit, PhD, MT-BC; Mary Fran Tracy, PhD, RN; Debra J. Skaar, PharmD; Jill L. Guttormson, PhD, RN; Kay Savik, MS
Effectiveness of a Bundled Intervention of Decolonization and Prophylaxis to Decrease Gram Positive Surgical Site Infections After Cardiac or Orthopedic Surgery: Systematic Review and Meta-analysis
Marin Schweizer, assistant professor, Eli Perencevich, professor, Jennifer McDanel, student research assistant, Jennifer Carson, research assistant, Michelle Formanek, student research assistant, Joanne Hafner, associate project director, Barbara Braun, project director, Loreen Herwaldt, professor
Cough resolution by 6 weeks was more likely when children were managed by an algorithm.
Chronic cough is a common complaint in primary care pediatrics and a difficult symptom for families. Researchers in Australia evaluated management of chronic cough using an algorithm based on available evidence (mostly nonrandomized trials) and expert consensus. They randomized 272 referred children (mean age, 4.5 years) with chronic cough (>4 weeks; median, 16 weeks) and without known chronic respiratory illness at five tertiary centers to receive early or delayed (about 3 weeks later) management according to an algorithm:
Active and Passive Smoking and Risk of Death from Pancreatic Cancer: Findings from the Japan Collaborative Cohort Study
Lin Y, Yagyu K, Ueda J, Kurosawa M, Tamakoshi A, Kikuchi S
David S. Ludwig, MD, PhD
Antibiotic Prophylaxis for Urinary Tract Infections After Removal of Urinary Catheter: Meta-analysis
Jonas Marschall, internist and infectious disease specialist, Christopher R Carpenter, internist and emergency medicine specialist, Susan Fowler, medical librarian, Barbara W Trautner, internist and infectious disease specialist for the CDC Prevention Epicenters Program
Maintenance therapy for metastatic breast cancer prolonged survival but increased hematologic toxicity.
How long chemotherapy should be continued in patients with metastatic breast cancer has been the subject of many clinical trials during the last 2 decades. In practice, patients frequently request "chemo breaks," and physicians often offer them, particularly when disease response has reached a plateau or when treatment toxicity is adversely affecting quality of life. If switching to an endocrine agent is an option, the decision is often less difficult. But when that is not an option, the appropriate duration of chemotherapy is unclear.
Current and Emerging Surveillance Strategies to Expand the Window of Opportunity for Curative Treatment After Surgery in Colorectal Cancer
Lin Koo S, Wen JH, Hillmer A, Cheah PY, Tan P, Tan IB
The Need for Access to Medicare Fee-for-Service Claims Data
John S. Toussaint, MD; Donald M. Berwick, MD
Shared Care Obesity Management in 3-10 Year Old Children: 12 Month Outcomes of HopSCOTCH Randomised Trial
Melissa Wake, paediatrician123, Kate Lycett, research assistant23, Susan A Clifford, research officer2, Matthew A Sabin, paediatric endocrinologist123, Jane Gunn, professor4, Kay Gibbons, dietitian12, Cathy Hutton, general practitioner4, Zoë McCallum, paediatrician13, Sarah J Arnup, biostatistician2, Gary Wittert, professor