CT Colonography: Expect the Best, Get the Worst

Patients randomized to receive CT colonography versus colonoscopy reported higher rates of embarrassment, pain, and overall burden than they had expected before the procedure.

Trainees need to conduct an estimated 450 colonoscopies to achieve a miss rate of <25% in 60-year-old patients.

An important issue in colonoscopy training is how to measure the detection abilities of trainees. In a recent study conducted at a single hospital in California, trainees had their adenoma miss rates measured by tandem colonoscopy. A total of 218 patients underwent a colonoscopy performed by a trainee and then a second colonoscopy performed by an attending endoscopist.

Low-Dose or High-Dose PPI Therapy After Endoscopic Hemostasis?

A small study conducted in Taiwan suggests that after successful endoscopic hemostasis in patients with bleeding peptic ulcers, low- and high-dose pantoprazole are equally effective.

Rabeprazole-Based Rescue Therapy for Helicobacter pylori Successful in Malaysia

After PPI-based triple therapy failed, most infections were eradicated with rabeprazole and amoxicillin.

Cancer Risk Increased in Relatives of Patients with Serrated Polyposis

Findings support evidence for an inherited component to the disease.

Risk Factors for Perforation with Endoscopic Mucosal Dissection

Tumor location in the upper stomach and tumor size >20 mm were predictors of perforation.

Elimination Diet Works for Eosinophilic Esophagitis in Adults

A six-food elimination diet led to symptom improvement in 94% of patients and complete histologic improvement in 64%.

Eosinophilic esophagitis (EoE) is increasingly recognized as a cause of dysphagia, food impaction, and heartburn. In children, a true elemental diet seems to be effective but is too unpalatable for routine use. A six-food elimination diet (milk, soy, egg, wheat, peanuts/tree nuts, and shellfish/fish) has shown moderate effectiveness in treating children with EoE but has not been well studied in adults.

Outcomes in Cirrhotic Patients with Variceal Bleeding Despite Primary Prophylaxis with a ?-Blocker

Even with the addition of endoscopic band ligation, such patients are at increased risk for recurrent bleeding and death.

Debunking the Notion That Proton-Pump Inhibitors Cause Bacterial Overgrowth

A large, retrospective study using glucose hydrogen breath testing found no association.