Effect of Home Based HIV Counselling and Testing Intervention in Rural South Africa: Cluster Randomised Trial

Tanya Doherty, senior specialist scientist, Hanani Tabana, senior scientist, Debra Jackson, professor, Reshma Naik, PhD student, Wanga Zembe, senior scientist, Carl Lombard, unit director biostatistics, Sonja Swanevelder, senior statistician, Matthew P Fox, professor, Anna Thorson, professor, Anna Mia Ekström, professor, Mickey Chopra, head of health section

Abstract

Objective To assess the effect of home based HIV counselling and testing on the prevalence of HIV testing and reported behavioural changes in a rural subdistrict of South Africa.

Design Cluster randomised controlled trial.

Setting 16 communities (clusters) in uMzimkhulu subdistrict, KwaZulu-Natal province, South Africa.

Participants 4154 people aged 14 years or more who participated in a community survey.

Intervention Lay counsellors conducted door to door outreach and offered home based HIV counselling and testing to all consenting adults and adolescents aged 14-17 years with guardian consent. Control clusters received standard care, which consisted of HIV counselling and testing services at local clinics.

Main outcome measures Primary outcome measure was prevalence of testing for HIV. Other outcomes were HIV awareness, stigma, sexual behaviour, vulnerability to violence, and access to care.

Results Overall, 69% of participants in the home based HIV counselling and testing arm versus 47% in the control arm were tested for HIV during the study period (prevalence ratio 1.54, 95% confidence interval 1.32 to 1.81). More couples in the intervention arm had counselling and testing together than in the control arm (2.24, 1.49 to 3.03). The intervention had broader effects beyond HIV testing, with a 55% reduction in multiple partners (0.45, 0.33 to 0.62) and a stronger effect among those who had an HIV test (0.37, 0.24 to 0.58) and a 45% reduction in casual sexual partners (0.55, 0.42 to 0.73).

Conclusions Home based HIV counselling and testing increased the prevalence of HIV testing in a rural setting with high levels of stigma. Benefits also included higher uptake of couple counselling and testing and reduced sexual risk behaviour.

Trial registration Current Controlled Trials ISRCTN31271935.