The Hepatic Cannabinoid 1 Receptor as a Modulator of Hepatic Energy State and Food Intake
Cooper ME, Regnell SE
Slow Progress
Richard Smith, MB, ChB, MSc, FRCPE; Tara McCready, MBA, PhD; Salim Yusuf, DPhil, FRCPC, FRSC
Coronary Artery Calcium Score Prediction of All Cause Mortality and Cardiovascular Events in People with Type 2 Diabetes: Systematic Review and Meta-analysis
Caroline K Kramer, endocrinology research fellow,
Bernard Zinman, professor of medicine,
Jorge L Gross, professor of medicine,
Luis H Canani, associate professor of medicine,
Ticiana C Rodrigues, associate professor of medicine,
Mirela J Azevedo, associate professor of medicine,
Ravi Retnakaran, associate professor of medicine
More evidence that the drug-antibody conjugate is effective and safe for patients with advanced disease
The recent FDA approval of the drug-antibody conjugate T-DM1 (trastuzumab emtansine, brand name Kadcyla) had been eagerly anticipated. Its arrival brings to the clinic a novel agent capable of delivering a cytotoxic to its target (human epidermal growth factor receptor 2 [HER2]–positive breast cancer) more effectively and with less toxicity than chemotherapy plus trastuzumab or other anti-HER2 agents such as lapatanib (JW Oncol Hematol Oct 23 2012).
Effect of Behavioural-educational Intervention on Sleep for Primiparous Women and their Infants in Early Postpartum: Multisite Randomised Controlled Trial
Robyn Stremler, assistant professor and adjunct scientist, Ellen Hodnett, professor, Laura Kenton, trial coordinator, Kathryn Lee, professor, Shelly Weiss, staff neurologist and assistant professor, Julie Weston, senior trial coordinator, Andrew Willan, senior scientist and professor
Bad Breast Cancer on the Rise in Young Women
In women aged 25 to 39, the incidence of stage IV disease has increased, on average, 2.07% per year from 1976 to 2009; no similar trend was observed in older women.
Matsuda E, Okabe K, Takahagi A, Hayashi T, Tanaka T, Sano F, Tao H
Comparison of Presenting Complaint vs Discharge Diagnosis for Identifying “ Nonemergency” Emergency Department Visits
Maria C. Raven, MD, MPH, MSc; Robert A. Lowe, MD, MPH; Judith Maselli, MSPH; Renee Y. Hsia, MD, MSc
Cardiovascular Events After Clarithromycin Use in Lower Respiratory Tract Infections: Analysis of Two Prospective Cohort Studies
Stuart Schembri, consultant respiratory physician, Peter A Williamson, consultant respiratory physician, Philip M Short, clinical lecturer in respiratory medicine, Aran Singanayagam, clinical research fellow, Ahsan Akram, clinical research fellow, Joanne Taylor, foundation doctor, Anika Singanayagam, clinical research fellow, Adam T Hill, consultant respiratory physician, honorary senior lecturer, James D Chalmers, clinical lecturer in respiratory medicine
Neurology Case Diagnosis: Involuntary Contractions and Lip Twitching
The diagnosis of the case presented on February 19, 2013, and a discussion of reader responses
