Seasonal Influenza Remains a Significant Healthcare Burden in Children
Influenza vaccine and antiviral agents are underutilized.
Chemotherapy Prolongs Survival in Patients With Cholangiocarcinoma
Chemotherapy significantly prolongs survival in patients with metastatic cholangiocarcinoma (CCA), according to a study presented here on March 1 at Canadian Digestive Diseases Week 2013 (CDDW).
A Balance Between Discovery and Delivery
William A. Zoghbi, MD; David R. Holmes, MD
Accuracy of the “Traffic Light” Clinical Decision Rule for Serious Bacterial Infections in Young Children with Fever: A Retrospective Cohort Study
Sukanya De, PhD student, Gabrielle J Williams, clinical researcher, Andrew Hayen, associate professor of biostatistics, Petra Macaskill, professor of biostatistics, Mary McCaskill, medical director, David Isaacs, senior staff specialist, Jonathan C Craig, senior staff specialist
The addition of docetaxel to androgen-deprivation therapy provides no benefit for patients with non-castrate disease.
Although androgen-deprivation therapy (ADT) remains the standard of care in metastatic prostate cancer, essentially all patients ultimately develop castration resistance and disease progression. Docetaxel (with prednisone) was FDA approved in 2004 for patients with castration-resistant disease after phase III trials demonstrated improvements in both overall survival and disease-related symptoms (e.g., N Engl J Med 2004; 351:1502). However, the optimal timing of docetaxel administration is undefined.
Hyaluronic Acid as a Marker of Hepatic Sinusoidal Obstruction Syndrome Secondary to Oxaliplatin-Based Chemotherapy in Patients with Colorectal Liver Metastases
van den Broek MA, Vreuls CP, Winstanley A, Jansen RL, van Bijnen AA, Dello SA, Bemelmans MH, Dejong CH, Driessen A, Olde Damink SW
Daniel P. Alford, MD, MPH
Income Inequality and 30 Day Outcomes After Acute Myocardial Infarction, Heart Failure, and Pneumonia: Retrospective Cohort Study
Peter K Lindenauer, associate professor of medicine, Tara Lagu, assistant professor of medicine, Michael B Rothberg, associate professor of medicine, Jill Avrunin, statistician, Penelope S Pekow, senior statistician, Yongfei Wang, lecturer in medicine, senior statistician, Harlan M Krumholz, Harold J Hines Jr professor of medicine
Transcatheter Arterial Catheter Embolization for Hepatocellular Cancer
TACE, plus radiofrequency ablation, was superior to RFA alone in patients with liver-confined disease.
Sepsis-associated Liver Injury: Incidence, Classification and the Clinical Significance
Kobashi H, Toshimori J, Yamamoto K
